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Journal of Applied Genetics 51(3), 2010, pp. 319-321

Chromosomal assignment of R-spondin genes in the donkey (Equus asinus, 2n = 62)

L. De Lorenzi, V. Genualdo, A. Perucatti, G. Pia Di Meo, L. Molteni, L. Iannuzzi, P. Parma


Abstract: R-spondins constitute a recently discovered small family of growth factors, and the evidence of their role in several developmental pathways is growing fast. In this work we describe the chromosomal location of the four RSPO genes in the donkey. Using horse BACs, we localized RSPO1 on EAS 5q23, RSPO2 on EAS 12q13, RSPO3 on EAS 24q26, and RSPO4 on EAS 15p13. Moreover, RSPO2, RSPO3, and RSPO4 are the first genes mapped on donkey chromosomes 12, 24, and 15, respectively.

Key words: BAC, donkey, FISH, mapping, RSPO1, RSPO2, RSPO3, RSPO4

Correspondence: P. Parma, UniversitB di Milano, Dipartimento di Scienze Animali, Sezione di Zootecnica Agraria, Via Celoria 2, 20133 Milano, Italy; e-mail: pietro.parma@unimi.it

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