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Journal of Applied Genetics 48(1), 2007, pp. 73-76

Cytogenetic mapping of DGAT1, PPARA, ADIPOR1 and CREB genes in the pig

Izabela Szczerbal, Li Lin, Monika Stachowiak, Agata Chmurzynska, Mariusz Mackowski, Andreas Winter, Krzysztof Flisikowski, Ruedi Fries, Marek Switonski


Abstract: In the present study we show FISH localization of 4 porcine BAC clones harbouring potential candidate genes for fatness traits: DGAT1 (SSC4p15), PPARA (SSC5p15), ADIPOR1 (SSC10p13) and CREB (SSC15q24). Until now the CREB and ADIPOR1 genes are considered to be monomorphic, DGAT1 is highly polymorphic, while for the PPARA gene only 1 SNP was identified. Assignment of the studied genes in relation to QTL chromosome regions for meat quality in pig chromosomes SSC4, SSC5, SSC10 and SSC15 is discussed.

Key words: pig, lipid metabolism, fatness traits, FISH, DGAT1, PPARA, ADIPOR1, CREB.

Correspondence: M. Switonski, Department of Genetics and Animal Breeding, August Cieszkowski Agricultural University of Poznan, Wolynska 33, 60-637 Poznan, Poland; e-mail: switonsk@jay.au.poznan.pl

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