JOURNAL OF
APPLIED GENETICS
        
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Contents



Journal of Applied Genetics 43(3), 2002, pp. 269-278

Statistical methods for microarray assays

Pawel KRAJEWSKI, Jan BOCIANOWSKI


Abstract: The paper shortly reviews statistical methods used in the area of DNA microarray studies. All stages of the experiment are taken into account: planning, data collection, data preprocessing, analysis and validation. Among the methods of data analysis, the algorithms for estimating differential expression, multivariate approaches, clustering methods, as well as classification and discrimination are reviewed. The need is stressed for routine statistical data processing protocols and for the search of links of microarray data analysis with quantitative genetic models.

Key words: DNA microarrays, data collection, statistical methods, planning experiments, data analysis, validation

Correspondence: P. KRAJEWSKI, Institute of Plant Genetics, Polish Academy of Sciences, ul. Strzeszynska 34, 60-479 Poznan, Poland, e-mail: pkra@igr.poznan.pl

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