JOURNAL OF
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Journal of Applied Genetics 42(4), 2001, pp. 503-507

Frequencies of alleles and genotypes of the PRNP gene in Polish Red, Czech Pied and Czech Black-and-White cattle

Irena VRTKOVA, Andrzej FILISTOWICZ, Ales DVORAK, Heliodor WIERZBICKI, Tadeusz SZULC


Abstract: Frequencies of alleles and genotypes of the PRNP gene in 65 Polish Red cows kept under a conservation programme and 52 randomly chosen cows of two Czech breeds: Czech Pied (42) and Black-and-White (10) were studied. All cows were at the age of 4 years or older. It was found that the frequency of allele 5 (5 copies of the octapeptide repeat) ranged from 0.11 (Polish Red) to 0.00 (Czech Black-and-White) whereas the frequency of allele 6 (6 copies of the octapeptide repeat) ranged from 1.00 (Czech Black and White) to 0.89 (Polish Red). The highest frequency was found for the homozygous genotype 6/6 (1.00 in Czech Black-and-White) and the lowest frequency was detected for the heterozygous genotype 6/5 (0.143). In the studied cows the genotype 5/5 was not found. The higher frequency of allele 5 in the native breeds and its lower frequency or lack of this allele in the populations intensively selected for high milk production may suggest that alleles of the PRNP gene may be associated with milk production.

Key words: allele frequency, BSE, cattle, PRNP gene.

Correspondence: A. FILISTOWICZ, Department of Genetics and Animal Breeding, Agricultural University, ul. Kozuchowska 7, 51-631 Wroclaw, Poland, e-mail: andrzej@gen.ar.wroc.pl