JOURNAL OF
APPLIED GENETICS
        
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Contents



Journal of Applied Genetics 42(2), 2001, pp. 205-209

A low-level X chromosome mosaicism in mares, detected by chromosome painting

Miroslawa WIECZOREK, Marek SWITONSKI, Fengtang YANG


Abstract: Fluorescence in situ hybridization with the use of the equine X whole chromosome painting probe was carried out on chromosome spreads originating from three mares with poor reproductive performance (infertility, miscarriage or stillbirth). The numbers of analysed spreads were high (105, 300 and 480) and in all three mares a low frequency of mosaicism was identified. The mares had the following karyotypes: 64,XX/63,X/65,XXX (93.6%/5.7%/0.7%), 64,XX/63,X (98.9%/1.1%) and 64,XX/63,X (94.3%/5.7%). The incidence and importance of the low percentage X chromosome mosaicism are discussed.

Key words: chromosome painting, horse, mosaicism, X chromosome paint, X monosomy.

Correspondence: M. Wieczorek, Department of Genetics and Animal Breeding, Agricultural University of Poznan, ul. Wolynska 33, 60-637 Poznan, Poland.