Journal of Applied Genetics 41(4), 2000, pp. 285-292
Frequent D-loop polymorphism in mtDNA enables genotyping of 1400-year-old human remains from
Monika ZELLER, Farhad MIRGHOMIZADEH, Heinz-Dieter WEHNER, Nikolaus BLIN
Abstract: Improvements of DNA extraction and amplification techniques presently enable
DNA analysis of ancient DNA (aDNA) from samples which range from several hundred
years of age up to possibly 5000 years. Taking advantage of the abundance of
mitochondrial DNA and its polymorphic D-loop sequence, ten individuals from multiple
burial sites of the Merowingian culture (South Germany), estimated to be
Key words: ancient DNA, kinship analysis, mtDNA sequencing.
Correspondence: M. ZELLER, Institute of Legal Medicine, University of Tubingen,
GartenstraBe 47, D�72074 Tubingen, Germany.